ISO/TR TECHNICAL REPORT 16379 First edition 2014-03-01 Tissue-engineered medical products Evaluation of anisotropic structure of articular cartilage using DT (Diffusion Tensor)-MR Imaging Produitsmedicauxabasedetissus- Evaluationdela structure anisotrope du cartilage articulaire en utilisant I'imagerie en tenseur de diffusion (IRM-TD) Reference number ISO/TR 16379:2014(E) LSO @ IS0 2014 I without license from IHS Not for Resale IS0/TR16379:2014(E) COPYRIGHTPROTECTEDDOCUMENT @ISO2014 All rights reserved. Unless otherwise specified, no part of this publication may be reproduced or utilized otherwise in any form written permission. Permission can be requested from either ISO at the address below or ISO's member body in the country of the requester. ISOcopyrightoffice Case postale 56:CH-1211 Geneva 20 Tel. + 41 22 749 01 11 Fax + 41 22 749 09 47 E-mail [email protected] Web www.iso.org Published in Switzerland @ IS0 2014 - All rights reserved networking permitted without license from IHS Not for Resale IS0/TR 16379:2014(E) Contents Page Foreword ..iv Introduction. ..V 1 Scope. .1 2 Terms and definitions ..1 3 Principle ..3 4 Diffusion tensor magnetic resonance imaging (DT-MRI) data observation in articular cartilage .3 4.1 DT-MRImeasurementprocess .3 4.2 Notes on setting of DT-MRI imaging parameters for articular cartilage 4 4.3 Measurement indices for structural evaluation of articular cartilage by DT-MRI ..5 Annex A (informative) Measurement Results ..10 Bibliography .23 iii lout license from IHS Not for Resale